Category Archives: External R&D

Atlas Venture 2024 Year In Review
November 18, 2024

“May you live in interesting times” – or so goes the phrase. In 1966, RFK Jr’s father famously used that quote to capture the turbulence of the times, and continued: “Like it or not, we live in interesting times. They

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IFM’s Hat Trick and Reflections On Option-To-Buy M&A
March 13, 2024

Today IFM Therapeutics announced the acquisition of IFM Due, one of its subsidiaries, by Novartis. Back in Sept 2019, IFM granted Novartis the right to acquire IFM Due as part of an “option to buy” collaboration around cGAS-STING antagonists for

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Atlas Venture 2023 Year In Review
November 17, 2023

2023 couldn’t end fast enough for most of us in biopharma; its been a tough year in the capital markets, and the industry is facing it’s fair share of headwinds. Fortunately, despite all that, great science and medicine continues to

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BioPharma M&A Drives More Efficient Resource Allocation
March 2, 2020

M&A is an omnipresent reality in the biopharma industry, from Big Pharma mega-mergers to smaller acquisitions of emerging startups. We’ve recently witnessed several large M&A transactions get closed or announced, including BMS-Celgene, Takeda-Shire, and AbbVie-Allergan; according to BMO Capital Markets

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Goldilocks And GMP
August 7, 2019

This blog was written by Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC. New therapeutic platforms, like those based on cell and gene therapy, provide potential to address diseases in new ways

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Nimbus Therapeutics Reaches Summit For Deal With Celgene
October 3, 2017

Today Nimbus and Celgene announced a significant partnership focused on autoimmune and inflammatory diseases. The alliance includes two pre-clinical autoimmune-focused programs in various stages of drug discovery. The most advanced program is a highly selective inhibitor of Tyk2, an immunokinase

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Innately Innovative: IFM Therapeutics Acquired By BMS
August 3, 2017

Today BMS announced the acquisition of IFM Therapeutics, an emerging biotech focused on modulating core innate immune pathways to treat cancer and autoimmune disease. As described in the press release, BMS will acquire the company for $300M upfront, with potentially

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Potential Breakthrough Option For Parkinson’s: LTI Partners With Allergan
January 9, 2017

Today Allergan announced a transformative deal with Lysosomal Therapeutics (LTI), an emerging biotech focused on Parkinson’s Disease through an understanding of human genetics and sphingolipid biology (here). This deal brings a new chapter for LTI as we move our lead

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Positive Impact Of External Sourcing On Pharma R&D Productivity
December 16, 2016

Pharma R&D productivity continues to be a critical issue for the industry. Making smart investments in R&D requires an understanding of the risk and return drivers across the product development cycle, as well as some good fortune. This week the

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Potential Silver Lining Of Pharma Price Pressure: More Biotech Deal-making?
September 14, 2016

The maelstrom around drug pricing has continued its fury over the past month, which has led to considerable volatility in the biopharma stock market. Investor fears of draconian price controls that will eliminate the return of investment from innovative pharmaceutical

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Neuroscience Deal Doublet: Both Quartet and Rodin Strike Transformative Partnerships
January 6, 2016

We’re excited to announce two new collaborations today from our neuroscience portfolio – Quartet with Merck (here) and Rodin with Biogen (here) – to advance their programs into early clinical development.  These are both young companies that we helped create

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Top Ten Most Engaging LifeSciVC Posts Of 2015
December 28, 2015

As 2015 comes to a conclusion, it’s a good time reflect on the year’s progress – celebrating the wins, thinking through the losses, and learning from both. One specific reflection of late regards this blog: I’ve looked back at the

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Seven Habits of Celgene’s Highly Successful Strategy
December 10, 2015

Over the past seven years, Celgene has emerged as one of the most active and creative deal-makers in the biopharma industry. The Boston Consulting Group’s Biopharma Partnering Survey and Benchmarking analysis examines BD activity and perceptions across the industry, and

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Cell And Gene Therapy: An “Outside-In” Technology Evolution
November 12, 2015

The exciting renaissance in cell and gene therapy over the past five years has yielded some of the most innovative medical advances in the industry’s pipeline today.  There are now multiple stories of patients getting “cured” of rare diseases, responding

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External Innovation: Force Multiplier For R&D
June 26, 2015

External models of R&D innovation are the rage in Pharma today, as they should be – the future of our industry depends on a great deal more rather than less collaboration. In a very healthy way, lots of experiments are

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