Recovering scientist turned early stage VC A biotech optimist fighting gravity

Building Korro Bio: A CEO’s Perspective on Innovation and Risk Management
June 12, 2025

By Ram Aiyar, CEO of Korro Bio, as part of the From The Trenches feature of LifeSciVC It has been an extraordinary journey so far and one that continues to humble, inspire and motivate me every day. I’ve had the

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“We Got This”:  Don’t Let Negativity Become a Self-fulfilling Prophecy
June 5, 2025

By Arthur Tzianabos, CEO of Lifordi Immunotherapeutics, as part of the From The Trenches feature of LifeSciVC It’s easy to jump on the ‘negative bandwagon’ these days when news in our world and industry is focused on doom & gloom.

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Biotech Wisdom Of The Crowds: Competition And Capitalism
May 28, 2025

Over 200 GLP1 obesity programs are in development today.  More than 300 PD1/PDL1 cancer programs exist.  Greater than 150 programs target each of CD19 and KRAS. Therapeutic crowding has ratcheted up the competitive intensity in biotech to new levels. While

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Information Flow In Growing Organizations: A Framework For Results
May 21, 2025

By Ankit Mahadevia, former CEO of Spero Therapeutics and Atlas alumni, as part of the From The Trenches of LifeSciVC I recently read Yuval Noah Hariri’s Nexus; what stuck with me was how a society uses information to create shared

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Boosters and Biologics: Is Space-Based Biomanufacturing Real?
May 14, 2025

By Cody Tranbarger, EIR at Atlas Venture, as part of the From The Trenches feature of LifeSciVC It’s an interesting time to be thinking about space. Just a few months ago, SpaceX captivated and inspired the world by catching a

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Frameworks for Decision-Making & Lessons Learned from “Failing Fast”
April 17, 2025

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Drug discovery and development is a long, and often fraught, journey – it typically takes more than a decade to progress from idea

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Biotech Venture Creation: The Benefits Of Scarcity
April 8, 2025

The equity markets have collapsed in 2025, the IPO window is closed, the FDA is in turmoil, the NIH is being gutted… and it’s a great time to start new biotech companies. Why?  Because there are so few being created

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Strategic Infrastructure in a Fragmenting World: Biotech in the Transition Zone
April 8, 2025

By Jason Campagna, CMO of Q32 Bio, as part of the From The Trenches feature of LifeSciVC We’re entering a phase shift in biotech—one that extends beyond molecules, pipelines, or even platforms. Tariff escalations, supply chain fractures, and a reassertion

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The Biotech Juggling Act: Keeping all the Balls in the Air
March 20, 2025

“When the going gets tough, the tough get going” By Ram Aiyar, CEO of Korro Bio, as part of the From the Trenches feature of LifeSciVC. It has been quite a start to the 2025 year. The sentiment around biotech

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 The Sweetest Thing
March 12, 2025

By Arthur Tzianabos, CEO of Lifordi Immunotherapeutics, as part of the From The Trenches feature of LifeSciVC Given everything going on in our world right now, I’ve been thinking a lot about the state of biotech innovation…particularly as we wrestle

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Pitfalls Of The Scarcity Mindset
February 28, 2025

By Ankit Mahadevia, serial biotech entrepreneur and former CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC I recently had an illuminating discussion with a seed-stage biotech Founder, who was reflecting after a hard and

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Dancing with the DGC: Structural Biology Meets Muscular Dystrophy
February 18, 2025

By Cody Tranbarger, EIR at Atlas Venture, as part of the From The Trenches feature of LifeSciVC For decades, muscular dystrophy has stubbornly persisted among the most intractable categories of human disease. Despite recent progress with AAV Gene Therapy and

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