Recovering scientist turned early stage VC A biotech optimist fighting gravity

Atlas XIV And Reflections On The VC Math Problem
December 5, 2024

Today we announced the closing of Atlas Venture Fund XIV, a $450M investment vehicle focused exclusively on early stage biotech investing. With the closing of Fund XIV, we’re privileged to be able to continue backing innovative new biotech companies for

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Atlas Venture 2024 Year In Review
November 18, 2024

“May you live in interesting times” – or so goes the phrase. In 1966, RFK Jr’s father famously used that quote to capture the turbulence of the times, and continued: “Like it or not, we live in interesting times. They

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Biotech Risk Cycles: Assets And Platforms
October 28, 2024

Today’s market likes products. Platforms aren’t in vogue anymore. Investors, especially in the public markets, only want late stage de-risked assets. Pharma only seems to be buying these kinds of asset. VCs need to focus on clinical stage companies. Or

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ESMO Reflections: Glimmers of Hope with the Next Wave of I-O Therapies?
October 10, 2024

By Jonathan Montagu, CEO of HotSpot Therapeutics, as part of the From The Trenches feature of LifeSciVC HotSpot’s trip to Barcelona for the recent European Society of Medical Oncology (ESMO) Annual Meeting was no ‘European Vacation,’ but it was certainly

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Reflections On My Experience As A Board Member
September 18, 2024

By Ivana Magovčević-Liebisch, CEO of Vigil Neuroscience, as part of the From The Trenches feature of LifeSciVC In an industry where boom and bust cycles occur regularly and 90 percent of drug candidates fail to reach the market, an outstanding

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Keeping It Simple: What Really Matters For Emerging Enterprises  
September 4, 2024

By Ankit Mahadevia, chairman of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC A common theme in startup literature is that by cutting a range of unnecessary tasks, a step-change in results will follow.  I’ve found

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A Biotech Midsummer’s Madness
August 21, 2024

By Arthur Tzianabos, CEO of Lifordi Immunotherapeutics, as part of the From The Trenches feature of LifeSciVC Greetings from Lake Winnipesaukee in NH where I am at this time every year. It’s midsummer and vacation time for me and the

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Medicinal Chemistry In The Age Of Artificial Intelligence
August 5, 2024

By Peter Tummino, CSO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC  “Over the next five to 10 years, our goal is to become a company that’s leading the world in personalized medicines, a company

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A Primer on Early-Stage Biotech VC
July 31, 2024

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC From the outside, one might assume all biotech venture capital (VC) firms are more similar than different. However, once you look under the

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Looking for Opportunities to Accelerate Clinical Research in Rare Diseases
July 17, 2024

By Mike Cloonan, Chief Executive Officer of Sionna Therapeutics, as part of the From The Trenches feature of LifeSciVC The drug development process in rare diseases is rife with challenges especially when companies target significant differentiation or first-in-class targets. Identifying

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A Molecular Biologist’s Advice For Life
July 1, 2024

Having just turned 50, I’ve been reflecting on my first half-century of late… many fun and impactful moments, a few regrets, and a life I’ve tried to live to the fullest. One thread that has run throughout it has been

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To B or Not to (Series) B
June 18, 2024

By Robert Clarke, CEO of Kinaset Therapeutics, as part of the From The Trenches feature of LifeSciVC Strategic considerations of when and how to consider raising additional capital to support clinical development in an improving but still volatile market. As

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