Recovering scientist turned early stage VC A biotech optimist fighting gravity

Thinking Boldly: Alkermes Acquires Rodin Therapeutics
November 18, 2019

Today Alkermes announced its acquisition of Rodin Therapeutics, a leader in the field of synaptic dysfunction and neuronal epigenetics. Alkermes extensive experience in CNS diseases made them an ideal partner for Rodin, and this acquisition helps expand Alkermes’ efforts into

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The Promise Of Precision Neuroscience And Launch Of Arkuda Therapeutics
November 14, 2019

Neuroscience has had a tough run of news lately. With Amgen deprioritizing neuro this year, Pfizer doing the same last year, and others like BMS, GSK, and AZ cutting back on CNS a few years earlier, it would seem dark

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Ode to Patients 
October 15, 2019

This blog was written by Samantha Truex, CEO of Quench Bio, as part of the From The Trenches feature of LifeSciVC. Due to meetings in London on a Friday and in Dortmund on the following Monday, I spent the weekend

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 Leave No Stone Unturned: A Pipeline Story
October 10, 2019

This blog was written by Deanna Petersen, CBO of AVROBIO (@dmp9818), as part of the From The Trenches feature of LifeSciVC. Building a leading gene therapy pipeline in under two years (and a lot of air miles): how to persevere

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Early Company Evolution – People, Pipeline, and Purse
September 16, 2019

This blog was written by Mark Manfredi, CEO of Kyn Therapeutics, as part of the From The Trenches feature of LifeSciVC. “Time flies when you’re having fun.” That’s how I feel as I reflect on the first three years of

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Navigating The Unknown: Practical Thoughts On A Team That Can Rise To The Occasion
September 5, 2019

This blog was written by Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC.  One of the joys of building a company is that meeting one’s milestones routinely places us in positions that

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The Creation Of Biotech Startups: Evolution Not Revolution
August 15, 2019

The startup paradigm for the creation and funding of new biotech companies has evolved enormously over the past two decades. Recently there’s been a pair of articles from Tech VCs about applying alternative models of company creation (here, here) to

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Goldilocks And GMP
August 7, 2019

This blog was written by Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC. New therapeutic platforms, like those based on cell and gene therapy, provide potential to address diseases in new ways

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Tips for Industry-Academia Collaboration
July 24, 2019

This blog was written by Samantha Truex, Atlas EIR and CEO of Quench Bio, as part of the From The Trenches feature of LifeSciVC. Some of the most promising and innovative research underlying biotech start-ups arises in research institutions.  It

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Of Microbes And Men
May 29, 2019

This blog was written by Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC. I am the CEO of Synlogic, a synthetic biology company, where the focus of our work is the development

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SPR994:  A Long Shot, With Lots Of Twists And Turns To Phase III
May 23, 2019

This blog was written by Ankit Mahadevia, CEO and founder of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC.  At Spero we are privileged to be enrolling our pivotal study for SPR994, our oral antibiotic with

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Biotech Startups And The Hard Truth Of Innovation
May 20, 2019

Gary Pisano’s recent Harvard Business Review piece, The Hard Truth About Innovative Cultures, beautifully frames up how innovative corporate environments are frequently misunderstood. Innovative startups aren’t just about being cool and nimble, having beer taps in the kitchen, or an

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