Recovering scientist turned early stage VC A biotech optimist fighting gravity

Playing To Win: Building A Position Of Strength In Biotech
July 8, 2021

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC When I play board games, I play to win. That requires thinking several moves ahead. In the game Risk, for instance, it’s not

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Targeted Protein Degradation: The First Proof-of-Mechanism in a Randomized, Placebo-Controlled Study
July 6, 2021

By Nello Mainolfi, PhD, Co-Founder, President and CEO of Kymera Therapeutics, as part of the From The Trenches feature of LifeSciVC. The inherent ability to combine the power of genetic-like knockdown with the flexibility of small molecules; the power to

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The First Born
June 22, 2021

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I was in the passenger seat, trying desperately not to reach for the grab handle, saying reassuring things but thinking ‘those mailboxes are really

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Rethinking Your Professional Health: Having An Executive Coach Is A Gift, Not A Gap
June 15, 2021

By Andrea DiMella, VP and Head of Talent at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Spring in New England is in full bloom. All around birds are chirping, flowers are blooming, and there is

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Biotech’s Relevancy Challenge In An Expanding Universe
June 1, 2021

The universe of public biotech companies has been growing for a decade, and increasingly so in the past few years as the IPO market has flourished. Hundreds of young aspiring biotechs have tapped into the public equity markets, swelling the

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The Biotech Job Market Is As Hot As The Housing Market
May 27, 2021

The biotech job market is a bit like the suburban housing market—red hot. It’s a buyer’s market, don’t waive your inspection rights! By Pamela L. Esposito, CBO of Replimune as part of the From The Trenches feature of LifeSciVC. It

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Moving Beyond the Conversation
May 24, 2021

Co-authored by Jodie Morrison and René Russo, former CEO of Cadent Therapeutics and CEO of Xilio Therapeutics, respectively.   Over the last 5 years, biotech executives have been increasingly focused on the importance of greater diversity in our companies. As two

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You Want To Be A CBO? Four Tips To Set You On Your Way
May 3, 2021

By Deanna Petersen, Chief Business Officer of AVROBIO, as part of the From The Trenches feature of LifeSciVC Most of the titles in a biotech C-suite are generally self-explanatory. The Chief Technical and Manufacturing Officer runs operations in CMC and

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The Unsung Heroes Of Entrepreneurial Companies
April 26, 2021

The role of the core in making an organization great and how we do right by them By Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC Small organizations are amazing for the

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Five Macro Risks To Biotech Coming Out of Washington
April 22, 2021

Despite saving the world from COVID, pharma and biotech are still in the crosshairs of many politicians. With many anti-Pharma politicians and regulators emboldened in the current environment, and with more aggressive tax and spending policy in the works, there

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Biotech Funding Tops The Charts Again
April 20, 2021

Another quarter, another set of all-time highs for biotech funding – and this surfeit of capital continues raises possible concerns about its disciplined deployment. Back in January, when reflecting on the strange paradox of 2020, all-time-highs were across the board:

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Reimagining The Workplace Post Pandemic
April 15, 2021

By Jonathan Montagu, CEO of HotSpot Therapeutics, as part of the From The Trenches feature of LifeSciVC Returning to work following the pandemic presents an opportunity to think creatively about how to re-configure the workplace.  CEO’s that I have spoken

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