Recovering scientist turned early stage VC A biotech optimist fighting gravity

Nucleic Acid Therapeutics: Don’t Hit the Panic Button
November 28, 2016

This blog was written by both Bill Marshall, CEO of MiRagen Therapeutics, and Ron Renaud, CEO of RaNA Therapeutics, as part of the From The Trenches feature of LifeSciVC. Recent news from Alnylam, Ionis, and Mirna Therapeutics regarding toxicity-related setbacks

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Biotech Venture Capital Mythbusting Redux
November 21, 2016

Venture capital has been on a good run over the past few years across a range of sectors; even with recent slowdown relative to 2014-2015, venture-backed investments remain above historic averages.  In fact, the first three quarters of 2016 alone

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Rebooting The Conversation
November 16, 2016

This blog was written by Jason Gardner, founding CEO of Magenta Therapeutics and Atlas Entrepreneur-in-Residence, as part of the From The Trenches feature of LifeSciVC. Imagine the conversation today between a patient and doctor on the decision to have a

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Option Or Warrant: Alternative Structures For A Future Acquisition
November 15, 2016

This blog was written by Samantha Truex, former CBO of Padlock Therapeutics and Atlas Entrepreneur-in-Residence, as part of the From The Trenches feature of LifeSciVC. The search for creative deal structures that strike a “win-win” balance is a noble one.

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Onboarding New Talent: Post-IPO Turnover Of Biotech Boards
October 31, 2016

A biotech’s Board often plays important roles in shaping the company’s success or failure: contributing strategic guidance, providing proper governance, stewarding fiduciary responsibilities, raising a startups’ profile, aiding business development, to name a few. Over the life of a biotech,

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Specialist Fund Flows Help Fuel The Biotech Capital Markets
October 17, 2016

Fund flows between sectors are a critically important dynamic in the equity capital markets: when net fund flows are positive, more demand for equity exists and stock price movement bias upwards; conversely, when fund flows are negative, the selling pressure

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Exploring Company Contributions To The Origination Of New Medicines
October 13, 2016

A new FDA approval marks a major milestone in the biopharmaceutical business; relatively few biopharma companies are ever able to lay claim to having discovered, developed, or marketed a recently approved medicine. As of mid-October, the FDA has approved 17

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Biotech IPOs: Outliers, Value Creation, And The Dispersion Of Returns
September 27, 2016

Although many wrote off the biotech IPO markets as moribund earlier in 2016, the sector has been quietly issuing a steady stream of new offerings. Despite the volatility related to drug pricing, and disastrous first six-weeks of the year, we’ve

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Building A Stronger Ecosystem to Combat Antimicrobial Resistance
September 26, 2016

This blog was written by Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC.  Relative to a decade ago, those of us that have spent time finding new ways to outsmart drug-resistant bacteria

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Saluting Biotech M&A: Onward And Upward
September 23, 2016

As larger Pharma externally-enables more of its pipelines, the cadence of biotech M&A appears to be accelerating, especially for early stage deals. Another week, another biotech acquisition in the news: Allergan has acquired two private and two public R&D-stage companies in just

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Beyond Biotech M&A: What Comes Thereafter
September 22, 2016

This post was written by Samantha Truex, former CBO of Padlock Therapeutics, as part of the From The Trenches feature of LifeSciVC. Biotech M&A is all the rage these days. Allergan has acquired four small companies in the past couple

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Re-Balancing Immunity via Regulatory T Cell Potentiation: Introducing Delinia
September 20, 2016

This blog is written by Michael Gladstone, Principal at Atlas, as part of the From The Trenches feature of LifeSciVC. Charles de Gaulle once asked, “How can you govern a country which has 246 varieties of cheese?” But that might seem

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