Recovering scientist turned early stage VC A biotech optimist fighting gravity

Evolution Of The Biotech IPO Markets From Busted To Booming
September 21, 2020

In the excitement of today’s biotech IPO market, and the bullish period since 2013, it’s almost hard to remember how painful the equity capital markets were back in the day. When I began my career in venture capital in 2004,

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(Do Not) Let The Chips Fall Where They May
September 2, 2020

By Pamela L. Esposito, CBO of Replimune, as part of the From The Trenches feature of LifeSciVC. “You gotta know when to hold ‘em, know when to fold ‘em, know when to walk away, know when to run…” Kenny Rogers’

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Kymera Debuts On The Public Markets
August 31, 2020

August continued to show the biotech market’s resilience in the face of the COVID pandemic with one of the biggest venture fund flows for the month ever, and a half a dozen IPOs. Kymera Therapeutics was one of those August

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Zooming in on What Matters!
August 17, 2020

This blog was written by Rene Russo, CEO of Xilio Therapeutics, as part of the From The Trenches feature of LifeSciVC. A lifetime ago, in May 2020, I had the honor of writing my first “From the Trenches” blog. I

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Leave a Ladder Down, Part Deux
July 20, 2020

By Samantha Truex, CEO of QuenchBio, as part of the From The Trenches feature of LifeSciVC I have been privileged to read and write for this LifeSciVC blog for a handful of years now.  One of my favorite editions is

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The Record-Breaking Biotech Funding Tsunami Of 1H2020
July 15, 2020

We’re half way through one of the craziest years in recent memory, with a raging viral pandemic, civil unrest and protests, staggering unemployment and economic woes, and invasive murder hornets. And yet, like the indefatigable Energizer bunny, the biotech market

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Grit At A Grand Scale: Cultivating Resilience At The Organizational Level
July 8, 2020

By Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC. “Hey, you know, breakdowns come. And breakdowns go. So what are you going to do about it? That’s what I’d like to know – Gumboots In an

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Nurturing A Culture Of “Smart Speed” To Bring Gene Therapy To The World
June 23, 2020

By Deanna Petersen, chief business officer at AVROBIO, and Georgette Verdin, chief human resources officer at AVROBIO, as part of the From The Trenches feature of LifeSciVC. As we approach our 5th anniversary and surpass our 125th hire, we have

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Leading and Learning Through Challenging World Events
June 18, 2020

By Jodie Morrison, CEO of Cadent Therapeutics, as part of the From The Trenches feature of LifeSciVC It’s been over three months since stay at home advisories and social distancing protocols abruptly arrived in Massachusetts. Calls for a return to

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Will Clinical Trials Make a House Call?
June 15, 2020

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I love to travel. While still in training in internal medicine, I earned extra money to fund trips abroad by covering for community-based general

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Controlling Your Destiny: Why Investment in Manufacturing Capabilities Makes Sense
May 28, 2020

By Philip Astley-Sparke, CEO of Replimune, as part of the From The Trenches feature of LifeSciVC. Manufacturing of medicines based on biology is complex. Viral vector manufacturing to produce gene therapy constructs, vaccines and oncolytic viruses is especially intricate. Most

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The Business Of Science
May 21, 2020

This blog was written by Jonathan Montagu, CEO and co-founder of HotSpot Therapeutics, as part of the From The Trenches feature of LifeSciVC. Today marks an important milestone for HotSpot Therapeutics as we announce our Series B financing, but it

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