Recovering scientist turned early stage VC A biotech optimist fighting gravity

Scaling Thoughtfully: The Art Of Sharing Responsibilities Across A Growing Team
July 27, 2021

By Ankit Mahadevia, CEO and Founder of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC. The opportunity for each member of a NewCo to take on multiple responsibilities selects early for people ready to help a

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Immuno-Oncology: The Comeback Kid
July 13, 2021

By Tim Reilly & Jonathan Montagu, CDO and CEO of HotSpot Therapeutics, as part of the From The Trenches feature of LifeSciVC Now 10 years into the golden era of immuno-oncology (I-O) following the first FDA approval of ipilimumab (anti-CTLA4)

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SPAC downpour continues
July 9, 2021

By Sam Truex, Venture Partner at Atlas Venture, as part of the From The Trenches feature of LifeSciVC. Holy cow, have we seen the rain lately – both downpours outside and a downpour of SPAC activity. In October 2020, Bruce

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Playing To Win: Building A Position Of Strength In Biotech
July 8, 2021

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC When I play board games, I play to win. That requires thinking several moves ahead. In the game Risk, for instance, it’s not

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Targeted Protein Degradation: The First Proof-of-Mechanism in a Randomized, Placebo-Controlled Study
July 6, 2021

By Nello Mainolfi, PhD, Co-Founder, President and CEO of Kymera Therapeutics, as part of the From The Trenches feature of LifeSciVC. The inherent ability to combine the power of genetic-like knockdown with the flexibility of small molecules; the power to

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The First Born
June 22, 2021

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I was in the passenger seat, trying desperately not to reach for the grab handle, saying reassuring things but thinking ‘those mailboxes are really

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Rethinking Your Professional Health: Having An Executive Coach Is A Gift, Not A Gap
June 15, 2021

By Andrea DiMella, VP and Head of Talent at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Spring in New England is in full bloom. All around birds are chirping, flowers are blooming, and there is

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Biotech’s Relevancy Challenge In An Expanding Universe
June 1, 2021

The universe of public biotech companies has been growing for a decade, and increasingly so in the past few years as the IPO market has flourished. Hundreds of young aspiring biotechs have tapped into the public equity markets, swelling the

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The Biotech Job Market Is As Hot As The Housing Market
May 27, 2021

The biotech job market is a bit like the suburban housing market—red hot. It’s a buyer’s market, don’t waive your inspection rights! By Pamela L. Esposito, CBO of Replimune as part of the From The Trenches feature of LifeSciVC. It

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Moving Beyond the Conversation
May 24, 2021

Co-authored by Jodie Morrison and René Russo, former CEO of Cadent Therapeutics and CEO of Xilio Therapeutics, respectively.   Over the last 5 years, biotech executives have been increasingly focused on the importance of greater diversity in our companies. As two

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You Want To Be A CBO? Four Tips To Set You On Your Way
May 3, 2021

By Deanna Petersen, Chief Business Officer of AVROBIO, as part of the From The Trenches feature of LifeSciVC Most of the titles in a biotech C-suite are generally self-explanatory. The Chief Technical and Manufacturing Officer runs operations in CMC and

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The Unsung Heroes Of Entrepreneurial Companies
April 26, 2021

The role of the core in making an organization great and how we do right by them By Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC Small organizations are amazing for the

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