Recovering scientist turned early stage VC A biotech optimist fighting gravity

It’s a Matter of Aligning on the Priorities
December 8, 2020

By Rene Russo, CEO of Xilio Therapeutics, as part of the From The Trenches feature of LifeSciVC Prioritization is a concept that we have become intimately aware of, given the continually blurred lines of personal and professional obligations in a

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Biotech: The Featherweight Champion Of The Markets
November 20, 2020

Biotech punches way above its weight-class, and that’s never been more apparent than in this pandemic and the race for a COVID vaccine. For those of us in biopharma, it feels like it’s a large and dynamic sector populated by

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Negotiating 101: Advice From The Trenches
October 27, 2020

Part 2: Gaining leverage – and using it wisely By Deanna Petersen, Chief Business Officer of AVROBIO, as part of the From The Trenches feature of LifeSciVC. In a recent blog post, I walked through my tips for reading your adversaries’

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Negotiating 101: Advice From The Trenches
October 22, 2020

Part 1: Maintaining your cool – while making your adversary sweat By Deanna Petersen, Chief Business Officer of AVROBIO, as part of the From The Trenches feature of LifeSciVC It’s back-to-school season, and that puts me in the frame of

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Hiring In A Syndemic
October 20, 2020

By Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC I have many fond memories of St Patrick’s Day—most of them involve marching in the parade with a plastic bag and a few

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It’s Raining Biotech SPACs!
October 15, 2020

SPACs are all the rage today. With the IPO market booming and public investors seeking better returns, blank check companies called “Special Purpose Acquisition Companies” (SPACs) have been fueling up their tanks and chasing down their merger targets. New ones

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The Power Of Hope: A Joint Perspective On Finding Balance In The Search For Life-Changing Therapies
October 13, 2020

By Joachim Boekelmann and Joshua Brumm, as part of the From The Trenches feature of LifeSciVC.   At first blush, we may seem an unlikely duo: An attorney for a global insurance company living with a rare form of muscular dystrophy

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Playing To Win: Scenario Planning For Binary Readouts In Biotech
October 8, 2020

By Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC Earlier this fall, we prepared to report Phase III data for tebipenem HBr, our oral medication that, if approved, could help 2.7M patients

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Evolution Of The Biotech IPO Markets From Busted To Booming
September 21, 2020

In the excitement of today’s biotech IPO market, and the bullish period since 2013, it’s almost hard to remember how painful the equity capital markets were back in the day. When I began my career in venture capital in 2004,

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(Do Not) Let The Chips Fall Where They May
September 2, 2020

By Pamela L. Esposito, CBO of Replimune, as part of the From The Trenches feature of LifeSciVC. “You gotta know when to hold ‘em, know when to fold ‘em, know when to walk away, know when to run…” Kenny Rogers’

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Kymera Debuts On The Public Markets
August 31, 2020

August continued to show the biotech market’s resilience in the face of the COVID pandemic with one of the biggest venture fund flows for the month ever, and a half a dozen IPOs. Kymera Therapeutics was one of those August

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Zooming in on What Matters!
August 17, 2020

This blog was written by Rene Russo, CEO of Xilio Therapeutics, as part of the From The Trenches feature of LifeSciVC. A lifetime ago, in May 2020, I had the honor of writing my first “From the Trenches” blog. I

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