Recovering scientist turned early stage VC A biotech optimist fighting gravity

It’s the People, Stupid:  Building and Maintaining a High Performance Corporate Culture
November 25, 2014

Building a performance based corporate culture is a key aspect of the biotech innovation business.  It can be easy to overlook this facet of company building as one focuses on determining the robustness of the new technology, refining your business

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A Billion Here, A Billion There: The Cost Of Making A Drug Revisited
November 21, 2014

The cost of making a new drug has grown to nearly $2.6B, according to the latest and greatest from Tufts Center for the Study of Drug Development (here).  That’s a big and almost unfathomable number.  Critics immediately pounced on it,

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The Biotech Cross-Over Phenom: Biomarker Of Quality?
November 7, 2014

As one of big drivers behind the recent IPO window, cross-over investing into private biotech companies by both mutual fund and hedge fund investors has become increasingly commonplace over the past couple years.  As described at the BIO Investor meeting

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Acquisitions As The Silent Partner In Biotech Liquidity: IPO vs M&A Exit Paths
October 27, 2014

With the biotech IPO window still open for business, and valuations of the recent classes of 2013 and 2014 remaining robust, all eyes have been focused on this part of the value chain.  Significant mezzanine pre-IPO rounds are getting done

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Soothing Chronic Pain: Quartet’s Debut
October 23, 2014

This blog was written by Kevin Pojasek, co-founder, President, and acting CEO of Quartet Medicine, as part of the “From the Trenches” feature of LifeSciVC.   Addressing unmet need in chronic pain In the mid-1990’s, the American Pain Society and the Veterans

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Cellular Immunotherapy & Unum Therapeutics: Out of Many, One
October 21, 2014

More exciting news has emerged from the immuno-oncology field over the past couple weeks from both Penn/Novartis and NCI/Kite.  The former released new CAR-T data, widely heralded as “unprecedented” in its efficacy: in a trial of relapsed, refractory ALL patients,

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Fueling Up To Attack Cancer: Two Big Startup Financings
October 14, 2014

Immuno-oncology, antibody-drug conjugates, and cancer metabolism are three of the hottest and potentially most transformative approaches in cancer research today, and have occupied center stage at recent oncology meetings like ASCO and AACR (here, here). The immuno-oncology (I/O) field has

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Synthetic Biology Meets The Microbiome: Synlogic
October 7, 2014

Today Synlogic announced that the Bill & Melinda Gates Foundation joined the Series A financing to help power up its platform around developing therapeutic microbes (here).  Combining compelling elements of two exciting fields – engineering organisms with synthetic biology and

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Should I Stay Or Should I Go? Big Pharma Execs Taking The Biotech Plunge
October 6, 2014

That’s the dilemma facing drug hunters as leadership roles in biotech become more and more attractive.  You may have noticed that more and more seasoned pharma executives are making the move from big pharma or big biotech to lead small

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Atlas Venture: The Next Chapter
October 2, 2014

Today we’re excited to announce a new chapter in the Atlas story – we are transitioning from our ‘two franchise, one firm’ diversified venture model into two specialized, independent firms focused on technology and life sciences investing, in order to better capture

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Atlas Wins A Rhodes’ Scholarship
September 29, 2014

Thrilled to announce today that Jason Rhodes is joining Atlas! Many of you already know Jason, but here’s the scoop. He was the President and CFO at Epizyme, where he was instrumental in architecting the company’s incredible journey from epigenetics drug discovery

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Talent: The Biggest Issue In Biotech Boardrooms Today
September 25, 2014

As with everything in life, it’s always about the people.  Bet the jockey, not the horse.  Great entrepreneurs and C-level executives are very hard to come by in R&D-intensive biotech companies, and its probably one of the biggest bottlenecks in

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