By Robert Clarke, CEO of Kinaset Therapeutics, as part of the From The Trenches feature of LifeSciVC It’s now been a couple of months since the SVB collapse and the scramble many of us faced during that tumultuous few weeks.

By Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC This time a quarter ago organizations large and small were in the thick of the “to hybrid or not to hybrid” debate. Each

By Jeb Keiper, CEO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC Forward Nimbus Therapeutics began 14 years ago.  The premise at the time was that putting computational chemistry in the primary position for new

Times remain tough for private biotech venture capital funding. Access to capital is more constrained than it’s been in years, and companies are starting to feel the pinch.  Yet, despite the pain after a cycle of excess, perhaps this return

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC It was the last thing our finance team needed; a vague email from the CEO on a Thursday afternoon.  They were working on the

By Mike Cloonan, CEO of Sionna Therapeutics, as part of the From The Trenches feature of LifeSciVC There are a lot of reasons to be excited about leading an early-stage biotech company. It’s a chance to be at the forefront

By Jonathan Montagu, CEO of HotSpot Therapeutics, as part of the From The Trenches feature of LifeSciVC The phrase ‘build it and they will come’ dates all the way back to the Old Testament, and in more recent times has

Science2Startup (S2S) is back!  In April 2020, we were planning the 3rd annual S2S conference for university-focused biotech entrepreneurship – but it was unfortunately scuttled by COVID. A subsequent event in 2021 was also precluded by the pandemic.  But as

By Bob Clarke, CEO of Kinaset Therapeutics, as part of the From The Trenches feature of LifeSciVC As I ride the Amtrak towards New York City for a series of meetings on Park Avenue with bankers/analysts, face-to-face (F2F) meetings are

By Ankit Mahadevia, CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC Biotwitter is great for healthy debates.  The most recent has been on the merits of the hybrid vs.an in-person model.  John Maraganore’s excellent

By Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC Earlier this month, I attended the J.P. Morgan 41st annual Healthcare Conference in San Francisco after a two-year hiatus. Despite the torrential rain

Today we’re thrilled to announce the acquisition of Nimbus’ allosteric Tyk2 autoimmune program by Takeda for up to $6 billion in an upfront and future milestones. As a potential best-in-class asset in the significant new therapeutic category of selective Tyk2