Recovering scientist turned early stage VC A biotech optimist fighting gravity

Immuno-Oncology: Scratching the Surface
January 8, 2015

Another day, another announcement about great data from immuno-oncology.  It’s clearly one of the hottest fields in biopharma today, and has been for a few years.  The opening paragraph of a recent Leerink report by Seamus Fernandez and team on

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Rekindling The Flame
December 18, 2014

This blog was written by Mike Gilman, Atlas’ EIR and CEO of Padlock Therapeutics, as part of the “From the Trenches” feature of LifeSciVC. I thought I was done with immunology. I’m not formally trained as an immunologist, but I fell for it hard

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Company Culture: Continuation On A LifeSciVC Theme
December 11, 2014

This blog was written by Jeff Hatfield, CEO of Vitae Pharmaceuticals, as part of the “From the Trenches” feature of LifeSciVC. Over the past two weeks in LifeSciVC, I read with great interest and appreciation the blogs of two friends of

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Deck The Halls With… Compensation Committees
December 10, 2014

It’s that time of year again: Santa is preparing his list of naughty and nice biotech management teams, and taking his recommendations to the Compensation Committee. As I’ve been sitting through several of these meetings already, I thought it would

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Riding The Biotech Roller Coaster Like A Pro: Some Observations
December 1, 2014

This blog was written by Ankit Mahadevia, Atlas EIR and c0-founder of Spero and Rodin Therapeutics, as part of the “From the Trenches” feature of LifeSciVC. As startup folks we are great at keeping our heads down and looking ahead; this

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It’s the People, Stupid:  Building and Maintaining a High Performance Corporate Culture
November 25, 2014

Building a performance based corporate culture is a key aspect of the biotech innovation business.  It can be easy to overlook this facet of company building as one focuses on determining the robustness of the new technology, refining your business

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A Billion Here, A Billion There: The Cost Of Making A Drug Revisited
November 21, 2014

The cost of making a new drug has grown to nearly $2.6B, according to the latest and greatest from Tufts Center for the Study of Drug Development (here).  That’s a big and almost unfathomable number.  Critics immediately pounced on it,

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The Biotech Cross-Over Phenom: Biomarker Of Quality?
November 7, 2014

As one of big drivers behind the recent IPO window, cross-over investing into private biotech companies by both mutual fund and hedge fund investors has become increasingly commonplace over the past couple years.  As described at the BIO Investor meeting

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Acquisitions As The Silent Partner In Biotech Liquidity: IPO vs M&A Exit Paths
October 27, 2014

With the biotech IPO window still open for business, and valuations of the recent classes of 2013 and 2014 remaining robust, all eyes have been focused on this part of the value chain.  Significant mezzanine pre-IPO rounds are getting done

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Soothing Chronic Pain: Quartet’s Debut
October 23, 2014

This blog was written by Kevin Pojasek, co-founder, President, and acting CEO of Quartet Medicine, as part of the “From the Trenches” feature of LifeSciVC.   Addressing unmet need in chronic pain In the mid-1990’s, the American Pain Society and the Veterans

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Cellular Immunotherapy & Unum Therapeutics: Out of Many, One
October 21, 2014

More exciting news has emerged from the immuno-oncology field over the past couple weeks from both Penn/Novartis and NCI/Kite.  The former released new CAR-T data, widely heralded as “unprecedented” in its efficacy: in a trial of relapsed, refractory ALL patients,

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Fueling Up To Attack Cancer: Two Big Startup Financings
October 14, 2014

Immuno-oncology, antibody-drug conjugates, and cancer metabolism are three of the hottest and potentially most transformative approaches in cancer research today, and have occupied center stage at recent oncology meetings like ASCO and AACR (here, here). The immuno-oncology (I/O) field has

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