Author Archives: Philip Astley-Sparke

By Philip Astley-Sparke, CEO of Replimune, as part of the From The Trenches feature of LifeSciVC. I recently stepped down after a six-year stint as Chairman of uniQure (NASDAQ: QURE). In the process of interviewing potential successors, one candidate observed

By Philip Astley-Sparke, CEO of Replimune, as part of the From The Trenches feature of LifeSciVC. One of the biggest elephants in the room regarding starting and scaling young companies is the tension, often healthy but sometimes detrimental, that exist

By Philip Astley-Sparke, CEO of Replimune, as part of the From The Trenches feature of LifeSciVC. Manufacturing of medicines based on biology is complex. Viral vector manufacturing to produce gene therapy constructs, vaccines and oncolytic viruses is especially intricate. Most