Recovering scientist turned early stage VC A biotech optimist fighting gravity

Ode to Scientists
April 1, 2021

By Samantha Truex, CEO of Quench Bio, as part of the From The Trenches feature of LifeSciVC In the fall of 2019, I wrote a blog called Ode to Patients.  As stresses from many directions have mounted over the past

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Strategy Sync vs. Time Sink with Your Board
March 25, 2021

By Rene Russo, CEO of Xilio Therapeutics, as part of the From The Trenches feature of LifeSciVC.  If we could quantify the time and money impact of the resources invested in quarterly Board meeting preparation, I wonder if we would

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Selective Allosteric TYK2 Inhibitors
March 18, 2021

Family Oddball, and a New Class of Safe Oral Autoimmune & Inflammatory Disease Treatment with Blockbuster Potential By Jeb Keiper, CEO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC. On day one of the JPM

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Personal Reflection: Empathy In The Workplace
March 16, 2021

Just before I chaired a Board meeting last year, I spent a frustratingly painful hour going through many of the uncomfortable details of my divorce process and a set of emotional custody issues with my lawyers. Immediately after hanging up,

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A Firsthand Covid Perspective
January 8, 2021

By Jeb Keiper, CEO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC. This blog is dedicated to the front-line healthcare workers, essential service workers, scientists, patients, and their families who confront COVID-19 every day, and

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The Biotech Paradox of 2020: A Year In Review
January 4, 2021

2020 was an incredibly paradoxical year for those of us in biotech: the striking dichotomy of simultaneously experiencing agonizing tragedy alongside buoyant optimism. It was truly a horrifically tragic year for humanity, and for America in particular.  As everyone knows,

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Beyond The Balance Sheet: Thinking Broadly About Dilution In Building A Transformative Biotech
December 16, 2020

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC Over the course of my career in healthcare, I’ve been fortunate to serve in a leadership role through four IPOs and even more

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The Elephant in the Room
December 10, 2020

By Philip Astley-Sparke, CEO of Replimune, as part of the From The Trenches feature of LifeSciVC. One of the biggest elephants in the room regarding starting and scaling young companies is the tension, often healthy but sometimes detrimental, that exist

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It’s a Matter of Aligning on the Priorities
December 8, 2020

By Rene Russo, CEO of Xilio Therapeutics, as part of the From The Trenches feature of LifeSciVC Prioritization is a concept that we have become intimately aware of, given the continually blurred lines of personal and professional obligations in a

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Biotech: The Featherweight Champion Of The Markets
November 20, 2020

Biotech punches way above its weight-class, and that’s never been more apparent than in this pandemic and the race for a COVID vaccine. For those of us in biopharma, it feels like it’s a large and dynamic sector populated by

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Negotiating 101: Advice From The Trenches
October 27, 2020

Part 2: Gaining leverage – and using it wisely By Deanna Petersen, Chief Business Officer of AVROBIO, as part of the From The Trenches feature of LifeSciVC. In a recent blog post, I walked through my tips for reading your adversaries’

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Negotiating 101: Advice From The Trenches
October 22, 2020

Part 1: Maintaining your cool – while making your adversary sweat By Deanna Petersen, Chief Business Officer of AVROBIO, as part of the From The Trenches feature of LifeSciVC It’s back-to-school season, and that puts me in the frame of

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