Recovering scientist turned early stage VC A biotech optimist fighting gravity

Playing The Waiting Game: A Tactical & Spiritual Guide
June 2, 2015

This blog was written by Ankit Mahadevia, co-founder of Spero, Synlogic, and Rodin Therapeutics, as part of the “From the Trenches” feature of LifeSciVC. The concept of “getting s#it done” is central to our lives as entrepreneurs. With time and capital

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ASCO 2015: Abstract Thoughts On Cancer And Competition
May 29, 2015

With the start of the American Society of Clinical Oncology meeting, all eyes in the biopharma investor community are on Chicago. Social media is alive with #ASCO15 tweets and companies big and small are firing out press releases. Signal from

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From Crawl to Sprint: The Race to Treat NASH
May 21, 2015

This blog was written by Rosana Kapeller, CSO of Nimbus Therapeutics, as part of the “From the Trenches” feature of LifeSciVC. Early this week, Intercept Pharmaceuticals announced the much awaited design of their Ph. 3 clinical trial of Obeticholic Acid (OCA)

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Reflections On Scientific Advisory Board Construction
May 19, 2015

This blog was written by Kevin Pojasek, co-founder and Acting CEO of Quartet Medicine and Atlas EIR, as part of the “From the Trenches” feature of LifeSciVC. “Most of the smartest people work somewhere else.” The famous Bill Joy quote, often

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BioPharma M&A: Capital Efficiency Drives Returns
May 15, 2015

Amidst lofty public markets and robust fund flows, it’s easy to forget the importance of equity capital efficiency in building new biotech companies. But like gravity, it’s a fundamental principle and rests at the heart of generating quality returns in

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To Tweet Or Not To Tweet, That Is The Question
May 13, 2015

This blog was written by Ron Renaud, CEO of RaNA Therapeutics, as part of the “From the Trenches” feature of LifeSciVC. Have you ever scrolled through your Twitter feed and found something distasteful posted about your company? You may be the

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Confronting Real(i)ty In Cambridge
May 6, 2015

This blog was written by Chuck Wilson, CEO of Unum Therapeutics, as part of the “From the Trenches” feature of LifeSciVC. This is an ongoing saga about finding a new home for my company, Unum Therapeutics. Google tells me that there

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Scorecard Of Biobuck M&A Earnouts
April 30, 2015

Milestone payments are an important risk-sharing component in today’s biopharma deal-making toolbox. As it’s a topic I’ve explored in the past (here, here), it’s an opportune time to revisit the stats for how they have performed recently. These contingent value transfers

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It’s The Antigens, Stupid
April 27, 2015

This blog was written by Michael Gladstone, Principal at Atlas Venture, as part of the “From the Trenches” feature of LifeSciVC. “A big asset of VC’s is pattern recognition. It is also often our biggest liability.”  An apt observation tweeted by

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Five Questions To Ask Your Investors Before You Take Their Money
April 22, 2015

This blog was written by Mike Gilman, CEO of Padlock Therapeutics and Atlas EIR, as part of the “From the Trenches” feature of LifeSciVC. Padlock Therapeutics is my second startup, and it’s not nearly as scary as the first one. Not

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Data Snapshot: Venture-Backed Biotech Financing Riding High
April 21, 2015

Biotech venture funding metrics continue at historic highs, highlighting that the robust financing environment in the public markets continues to fuel the private markets as well. Last week the quarterly Thomson Reuters data on venture capital funding came out via

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Atlas X: Accelerating Biotech Venture Creation
April 17, 2015

Earlier this week Atlas Venture closed Fund X at $280M, completing our transition to a biotech-only venture firm. After announcing the split of our life science and technology franchises in October 2014 (here), we embarked on the hard work of

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