Recovering scientist turned early stage VC A biotech optimist fighting gravity

Buying Time in 2014: Comparative Holding Periods For VC-Backed M&A Events
March 13, 2015

Over the past decade, in contrast to widely held misperceptions, the Biotech sector has witnessed time-to-IPO metrics very similar to other venture sectors, as I recently blogged on regarding the 2014 IPO Class (here). What wasn’t covered in the prior post was

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Nature Biotech Honors Some Of 2014’s Best Academic Startups
March 6, 2015

This afternoon Nature Biotechnology published its annual review of the “some of the best that academic research had to offer the startup world in 2014.” The article, in the March 2015 issue, covers the editors’ selections of the top startups

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Rare Diseases, Rare Opportunities
March 4, 2015

Last week on February 28th – as I sat down to write this short blog– was Rare Disease Day 2015. Rare diseases, and there are estimated to be 7000 of them, impact almost 30 million people in the US alone, according to

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Tortoise & Hare Revisited: “Time To IPO” For VC-Backed Startups
February 24, 2015

Getting a drug from discovery to market requires more than a dozen years, so you just can’t do biotech in a 10-year venture fund – it just takes too long, right?  Fortunately, wrong.  The data just don’t support this premise, although this

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Public Pool Or Private Beach
February 23, 2015

Three years ago, I was walking across One Kendall Square in pursuit of a late lunch and bumped into a friend – another biotech CEO. I was a year into my role as CEO of Idenix, a publicly traded biotech

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Better Living Through T-cells
February 19, 2015

Every week it feels like there’s yet another big event happening in the engineered T-cell therapy space. Recently it’s been biotech-pharma partnering (link). Before that it was the biggest biotech IPO of the year (link). And before that, it was

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Data Snapshot: Dwarfed By Big Pharma, Biotech By The Numbers
February 16, 2015

Biotech fills the news these days – whether it’s the announcement of exciting new clinical data, another high-flying IPO, or a big M&A deal. Amidst the significant “share of voice” in the coverage of young and emerging biotech in the

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Learnings From a Reluctant Entrepreneur
February 11, 2015

I am a scientist by vocation and training and an entrepreneur by accident.  I got into the business of starting companies when I decided almost a decade ago that I wanted to work on a new crazy therapeutic modality and the

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Where Does All That Biotech Venture Capital Go?
February 9, 2015

Venture capital investing in biotech has long been hard to disaggregate: how much goes to “early stage” vs “late stage”, how much goes to CNS vs oncology, discovery vs Phase 3, etc… Today BIO’s David Thomas and Chad Wessel have

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Data Snapshot: VC-Backed BioPharma M&A 2014
February 3, 2015

Similar to this time last year, when IPOs were capturing everyone’s attention, M&A in biotech has been delivering real value.  This morning HBM Partners released their outstanding report on BioPharma M&A in 2014 (here), and the conclusions are in line

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Infusing Biotech With Young Blood
January 30, 2015

This blog was written by Michael Gladstone, Principal at Atlas Venture, as part of the “From the Trenches” feature of LifeSciVC. Youth is often well represented among entrepreneurs – except in biotech. William Osler, founder of Johns Hopkins University and the

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Venture-Backed Biotech Today: Reflections On Exits, Funding, and Startup Formation
January 22, 2015

Biotech is definitely red-hot, and has been for the past eight quarters. Immuno-oncology, cancer metabolism, gene therapy, orphan diseases, NASH, autoimmune – there’s a broad range of disease settings that are capturing the excitement and imagination of investors today. With some

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