Author Archives: Aoife Brennan

By Aoife Brennan, former CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I have recently completed a turn around the biotech sun: a seven-year assignment at Synlogic that ended this year when an early readout

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I remember vividly my first vacation with the man who would be my husband.  In the days before Airbnb and on-line travel websites, he

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC It was the last thing our finance team needed; a vague email from the CEO on a Thursday afternoon.  They were working on the

By Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC Earlier this month, I attended the J.P. Morgan 41st annual Healthcare Conference in San Francisco after a two-year hiatus. Despite the torrential rain

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC  A couple of years ago, my husband returned from a business trip with a random gift for me. He was running through an airport

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC. From the first time I heard the story of the American chestnut, I was fascinated. It is a story with threads from history, ecology,

By Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC The COVID-19 pandemic has upended life as we know it. Given so much uncertainty, it is a normal human impulse to want some

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I was in the passenger seat, trying desperately not to reach for the grab handle, saying reassuring things but thinking ‘those mailboxes are really

By Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC I have many fond memories of St Patrick’s Day—most of them involve marching in the parade with a plastic bag and a few

By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I love to travel. While still in training in internal medicine, I earned extra money to fund trips abroad by covering for community-based general

This blog was written by Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC. I have never participated in trench warfare and I am sure it was pretty grim for those who lived and

This blog post was written by Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC. My first job at a public company was when I joined Biogen or Biogen Idec as it was then

This blog was written by Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC. New therapeutic platforms, like those based on cell and gene therapy, provide potential to address diseases in new ways

This blog was written by Aoife Brennan, CEO of Synlogic Therapeutics, as part of the From The Trenches feature of LifeSciVC. I am the CEO of Synlogic, a synthetic biology company, where the focus of our work is the development

This blog was written by Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC. It was apparently random, although I secretly suspect it was karmic punishment for my lack of imagination in writing the

This blog was written by Aoife Brennan, CEO of Synlogic, as part of the From The Trenches features of LifeSciVC. A lot has been written about the biotech talent war in the Boston area including the availability of talent as