Author Archives: Josh Brumm

Lessons Learned on Preparing to Weather the Inevitable Challenges in Biotech
September 15, 2022

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC By all accounts, 2022 did not start according to plan for the biotech industry. The U.S. economy and growth stocks struggled with the

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Empowering Therapeutic Advances With Early Patient Engagement
October 7, 2021

By Josh Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC One morning in early June I was reading my LinkedIn feed and saw something that caught my eye – a university was establishing

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Playing To Win: Building A Position Of Strength In Biotech
July 8, 2021

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC When I play board games, I play to win. That requires thinking several moves ahead. In the game Risk, for instance, it’s not

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Scaling Culture With Growth: How to maintain your startup’s “special sauce”
April 8, 2021

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC I’ve been thinking a lot about growth, and for good reason: Dyne is in the midst of a significant scale-up. We expanded our

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Beyond The Balance Sheet: Thinking Broadly About Dilution In Building A Transformative Biotech
December 16, 2020

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC Over the course of my career in healthcare, I’ve been fortunate to serve in a leadership role through four IPOs and even more

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The Power Of Hope: A Joint Perspective On Finding Balance In The Search For Life-Changing Therapies
October 13, 2020

By Joachim Boekelmann and Joshua Brumm, as part of the From The Trenches feature of LifeSciVC.   At first blush, we may seem an unlikely duo: An attorney for a global insurance company living with a rare form of muscular dystrophy

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Ordinary People Achieving The Extraordinary: Lessons In Leadership From The Court To The C-suite
April 30, 2020

This blog was written by Josh Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC. I stood in front of 15 skeptical parents and prepared to sell them on an improbable mission. They had

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